Van de Ven Double Halts The Toffees' Run at Brand New Home Ground
The Dutch defender emerged as the initial defender to net two goals in a English top-flight match for Spurs since the Belgian defender in spring 2013.
Match summary
The Spurs defender heads into the net twice in opening period
Everton's Jake O'Brien has goal disallowed after VAR review
Pape Matar Sarr nets third in dying moments
The defeat is Everton's initial at Hill Dickinson Stadium
The Tottenham defender found the net on two occasions as Tottenham prolonged their unbeaten run in away games in the Premier League and delivered Everton their first defeat at their new home.
The Toffees were unbeaten in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having left their historic home behind after 133 years at the end of last season.
But Tottenham's leader the Dutchman pounced on two occasions from corners in the opening 45 minutes to put their impressive record at risk, and they were unable to turn it around before the midfielder - assisted by ex-Everton forward Richarlison - nodded in a final goal to put the game to bed.
The Everton defender thought he had equalized the scores five minutes after the defender's first goal, directing a powerful header past Guglielmo Vicario from an Everton corner.
Beto, in the meantime, missed a number of opportunities, while Vicario made a series of fine saves to guarantee Tottenham went five away games without defeat in the English top flight.
But the VAR intervened, instructing Craig Pawson to review the score on the pitchside monitor and the official ruled that the winger and the attacker were in an illegal position and had interfered with the Tottenham goalkeeper.
This victory moves Thomas Frank's team into third place in the Premier League, a handful of points off local foes and leaders Arsenal.
Everton stay 14th and sit half a dozen points clear of the drop zone.
Spurs breakdown: The defender fulfils role at each end of the field
Following a drab midweek performance in the European competition against the French side, where they mustered a only attempts on goal, Frank chose Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The summer signing was failed to influence the game before being replaced for the substitute after an hour on the pitch, but it turns out he proved unnecessary in the end.
Defender Van de Ven converted into an attacking force to be feared.
Spurs' first goal came from a well-worked corner routine, with the midfielder directing the ball toward the face of goal for an free the defender to score.
And the captain - filling in as captain in the Argentine's absence - added his next goal in added time as he outjumped Jordan Pickford to head home.
Van de Ven was just as outstanding in defensive duties, combining well with his defensive colleague as the pair dealt superbly with the numerous deliveries thrown their way by Everton.
Everton analysis: Toffees missing finishing touch
The club's new home had been a fortress, but it seems the freshness may have worn off slightly and supporters flocked to the gates after Sarr's third for Spurs.
The end in Everton's unbeaten home run won't be a major worry for David Moyes, but their attacking woes will be.
Beto and Thierno Barry - the Toffees' pair of recognised centre-forwards - had netted only one league goal combined before Sunday's match.
And they were unable to contribute to that poor tally on a damp and dreary evening on Merseyside.
The striker's form was summed up when he opted to bicycle-kick a clear chance from close range, even with having space and opportunity to reposition for a simpler shot that would have challenged the keeper.
Barry, as well, was unable to make an impact after coming on for Beto in the second half.
It wasn't for a lack of opportunity. Most of the home side's offensive moves came through the winger and the forward, who relentlessly delivered threatening balls into the Tottenham penalty area.
Upcoming fixtures for both teams?
Everton: Moyes' men travel to the Stadium of Light in the Premier League on Monday, 3 November at 8 PM.
Spurs: The London club travel to Newcastle's ground on late October for their fourth-round League Cup match against the Magpies.